Use caution in the presence of respiratory disorders ("silent
may develop); glaucoma, prostatic hypertrophy (anticholinergic effects
may exacerbate glaucoma and urinary retention); epilepsy or history of
epilepsy (drug lowers seizure threshold); breast cancer (elevations in
prolactin may stimulate a prolactin-dependent tumor); thyrotoxicosis;
peptic ulcer, decreased renal function; myelography within previous 24 h or scheduled within 48 h; exposure to heat or phosphorous insecticides; lactation; children younger than 12 y, especially those with chickenpox, CNS infections (children are especially susceptible to dystonias that may confound the diagnosis of Reye's syndrome); allergy to aspirin if giving the 1-, 2-, 5-, and 10-mg tablets (these tablets contain tartrazine).
In veterinary medicine , selegiline is sold under the brand name Anipryl (manufactured by Zoetis ). It is used in dogs to treat canine cognitive dysfunction and, at higher doses, pituitary -dependent hyperadrenocorticism (PDH).   Canine cognitive dysfunction is a form of dementia that mimics Alzheimer's disease in humans. Geriatric dogs treated with selegiline show improvements in sleeping pattern, reduced incontinence, and increased activity level; most show improvements by one month.   Though it is labeled for dog use only, selegiline has been used off-label for geriatric cats with cognitive dysfunction.